SCHEMBL7473012

SCHEMBL7473012

CCCCCCCCCCCCCCCCCCNC(=O)N1CC(C(=O)NC)CCC1CCON(C=O)CCCN(C)C

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
BCHE P06276 2/20 0.36
GNAI3 P08754 2/20 0.32
GNAO1 P09471 2/20 0.32
GNAI1 P63096 2/20 0.32
NAAA Q02083 1/20 0.32
DNM1 Q05193 1/20 0.32
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7479322 0.91 DNM1 (0.33) GNAI3GNAO1GNAI1NAAADNM1
SCHEMBL7480069 0.91 LMNA (0.35) BCHEGNAI3GNAO1GNAI1NAAA
SCHEMBL7477983 0.91 DNM1 (0.32) GNAI3GNAO1GNAI1NAAADNM1
SCHEMBL7473017 0.84 BCHE (0.39) BCHEDNM1
SCHEMBL7472660 0.83 DPP4 (0.35) NAAADNM1EPHX2
Hydrochloric Acid SCHEMBL7478947 0.82 DPP4 (0.34) GNAI3GNAO1GNAI1NAAADNM1
SCHEMBL7478133 0.80 DNM1 (0.35) GNAI3GNAO1GNAI1DNM1EPHX2
SCHEMBL7473775 0.80 DNM1 (0.37) NAAADNM1
SCHEMBL7475403 0.79 DNM1 (0.33) GNAI3GNAO1GNAI1DNM1EPHX2
SCHEMBL7477703 0.79 DNM1 (0.32) GNAI3GNAO1GNAI1DNM1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0933361-B1 1,2-Di-substituted piperidine derivatives as hair growth promoter SHISEIDO CO LTD (JP) 2002-03-27 EP disclosed
US-6057337-A USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS SHISEIDO CO., LTD. (JP) 2000-05-02 US disclosed
EP-0933361-A1 1,2-Di-substituted piperidine derivatives as hair growth promoter SHISEIDO COMPANY LIMITED (JP) 1999-08-04 EP disclosed