Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | VDR | P11473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469634 | 0.85 | KDM4E (0.43) | KDM4ELMNANFKB1SMN1; SMN2MEN1 | |
| SCHEMBL7469625 | 0.85 | KDM4E (0.43) | KDM4ELMNANFKB1SMN1; SMN2MEN1 | |
| SCHEMBL1048487 | 0.76 | KDM4E (0.58) | KDM4ELMNASMN1; SMN2MEN1CYP1A2 | |
| SCHEMBL12210156 | 0.75 | MEN1 (0.44) | KDM4EVDRNFKB1SMN1; SMN2MEN1 | |
| SCHEMBL10642457 | 0.75 | RPS6KA5 (0.49) | KDM4EVDRLMNANFKB1SMN1; SMN2 | |
| SCHEMBL17279262 | 0.75 | KDM4E (0.50) | KDM4ELMNANFKB1SMN1; SMN2MEN1 | |
| SCHEMBL3616241 | 0.73 | KDM4E (0.65) | KDM4EVDRLMNANFKB1SMN1; SMN2 | |
| SCHEMBL13273926 | 0.73 | HAT1 (0.39) | KDM4EVDRLMNASMN1; SMN2MEN1 | |
| SCHEMBL10971739 | 0.72 | KDM4E (0.48) | KDM4ELMNANFKB1SMN1; SMN2MEN1 | |
| SCHEMBL13274129 | 0.72 | HAT1 (0.36) | KDM4EVDRLMNANFKB1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771796-B1 | Substituted S-triazines and process for their preparation | AGFA GEVAERT (BE) | 2002-06-19 | — | — | EP | disclosed |
| EP-0771796-A1 | Substituted S-triazines and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-07 | — | — | EP | disclosed |