SCHEMBL1048487

SCHEMBL1048487

CCn1c(C)nc2cc(Cl)c(Cl)cc21

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.58
RAD52 P43351 1/20 0.58
DCTPP1 Q9H773 2/20 0.57
TDP1 Q9NUW8 1/20 0.53
KMT2A Q03164 3/20 0.49
CCNT1 O60563 1/20 0.49
CDK9 P50750 1/20 0.49
LMNA P02545 4/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
TSHR P16473 1/20 0.47
HTT P42858 4/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CYP1A2 P05177 1/20 0.46
GAA P10253 1/20 0.46
MEN1 O00255 1/20 0.45
MAPT P10636 1/20 0.45
RAB9A P51151 1/20 0.43
HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30389867 0.86 KDM4E (0.53) KDM4ERAD52DCTPP1TDP1KMT2A
SCHEMBL24463170 0.86 KDM4E (0.53) KDM4ERAD52DCTPP1TDP1KMT2A
SCHEMBL11531138 0.84 KDM4E (0.50) KDM4ERAD52DCTPP1TDP1KMT2A
SCHEMBL11810252 0.82 KDM4E (0.49) KDM4ERAD52DCTPP1TDP1KMT2A
SCHEMBL11555842 0.81 KDM4E (0.51) KDM4ERAD52DCTPP1TDP1KMT2A
SCHEMBL16806057 0.81 CYP1A2 (0.60) KDM4ERAD52DCTPP1TDP1KMT2A
SCHEMBL6970745 0.80 PGK1 (0.50) KDM4ERAD52DCTPP1TDP1KMT2A
SCHEMBL6969528 0.80 PGK1 (0.50) KDM4ERAD52DCTPP1TDP1KMT2A
SCHEMBL17279262 0.80 KDM4E (0.50) KDM4ERAD52DCTPP1KMT2ACCNT1
SCHEMBL13400201 0.80 DCTPP1 (0.52) KDM4ERAD52DCTPP1TDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10110107-A None JP disclosed
JP-4059874-A None JP disclosed
CN-110863348-A Antibacterial fabric and production method thereof 江苏箭鹿毛纺股份有限公司 2020-03-06 CN disclosed
US-9709907-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-07-18 US disclosed
US-9709907-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-07-18 US disclosed
US-9500966-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-11-22 US disclosed
US-9500966-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-11-22 US disclosed
US-20150362848-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-12-17 US disclosed
US-20150362848-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-12-17 US disclosed
US-20150093693-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-04-02 US disclosed
US-4948843-A OPTICALLY CLEAR COLORED FILMS; IMAGING, PHOTOGRAPY AND SLOAR APPARATUS; CHEMICAL RESISTANCE EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed
US-4877723-A EMULSION LAYER CONTAINING AN ALKYNYL-SUBSTITUTED HETEROCYCLIC QUATERNARY AMMONIUM SALT; DIRECT POSITIVES; REVERSAL FUJI PHOTO FILM CO., LTD. (JP) 1989-10-31 US disclosed
US-4859579-A Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-08-22 US disclosed
US-4828973-A DIRECT POSITIVES WITH REVERSAL PROPERTIES FUJI PHOTO FILM CO., LTD. (JP) 1989-05-09 US disclosed
EP-0276842-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1988-08-03 EP disclosed
US-4740455-A Heat developable light-sensitive material containing polymethine FUJI PHOTO FILM CO., LTD. (JP) 1988-04-26 US disclosed
US-4539408-A Process for the preparation of sulphoalkyl quaternary salts AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1985-09-03 US disclosed
US-4524128-A HEAT-BLEACHABLE CYANINE DYES, COLORLESS BACKGROUNDS EASTMAN KODAK COMPANY (US) 1985-06-18 US disclosed
US-4375508-A ACETHYLENIC HYDROCARBON CHAIN EASTMAN KODAK COMPANY (US) 1983-03-01 US disclosed
US-4283488-A SILVER HALIDE EMULSIONS EASTMAN KODAK COMPANY (US) 1981-08-11 US disclosed