Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7476167 | 0.84 | ALDH1A1 (0.30) | — | |
| SCHEMBL7468914 | 0.84 | ALDH1A1 (0.30) | — | |
| SCHEMBL7477441 | 0.81 | ALDH1A1 (0.36) | — | |
| SCHEMBL7466109 | 0.78 | — | — | |
| SCHEMBL7479494 | 0.71 | — | — | |
| SCHEMBL7469691 | 0.67 | — | — | |
| SCHEMBL14876121 | 0.60 | NR1H2 (0.60) | — | |
| SCHEMBL14789789 | 0.56 | GSK3A (0.59) | AKT1 | |
| SCHEMBL23452411 | 0.56 | NR1H2 (0.44) | — | |
| SCHEMBL14789791 | 0.55 | ALDH1A1 (0.55) | AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214325-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001019831-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 2001-03-22 | — | — | WO | disclosed |