Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | DAO | P14920 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6152982 | 0.81 | MAPT (0.40) | MAPTMEN1ALDH1A1KMT2ANCEH1 | |
| Hydrochloric Acid SCHEMBL6610508 | 0.79 | MAPT (0.39) | MAPTMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL6612802 | 0.78 | ALDH1A1 (0.41) | MAPTMEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL6610237 | 0.77 | MAPT (0.35) | MAPTALDH1A1RAB9AKMT2A | |
| SCHEMBL10715629 | 0.74 | — | — | |
| SCHEMBL3212809 | 0.71 | KDM4E (0.44) | MAPTDAOMEN1ALDH1A1KMT2A | |
| SCHEMBL9025506 | 0.69 | KMT2A (0.36) | MAPTMEN1ALDH1A1RAB9AKMT2A | |
| SCHEMBL1551324 | 0.67 | CA12 (0.41) | MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL4707547 | 0.67 | TDP1 (0.31) | — | |
| SCHEMBL1617947 | 0.67 | MAPT (0.45) | MAPTMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200426-A1 | SUBSTITUTED THIENE-3-YL-SULFONYL AMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | Bayer Aktiengesellschaft (DE) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001005788-A1 | SUBSTITUTED THIENE-3-YL-SULFONYL AMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-25 | — | — | WO | disclosed |