Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6610508 | 0.98 | MAPT (0.39) | MAPTKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL6610237 | 0.84 | MAPT (0.35) | MAPTKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL6612802 | 0.82 | ALDH1A1 (0.41) | MAPTHSD17B10HPGDALDH1A1GAA | |
| SCHEMBL7473336 | 0.81 | MAPT (0.32) | MAPTALDH1A1KMT2AMEN1NCEH1 | |
| SCHEMBL6615690 | 0.81 | KDM4E (0.40) | MAPTKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL6610576 | 0.81 | KDM4E (0.37) | MAPTKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL6151863 | 0.78 | MAPT (0.36) | MAPTKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL10715629 | 0.76 | — | — | |
| SCHEMBL765304 | 0.72 | KDM4E (0.44) | MAPTKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL1617947 | 0.72 | MAPT (0.45) | MAPTKDM4EHSD17B10HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1598351-A1 | Substituted N-pyrimidinyl-N'-thienyl(amino)sulfonylureas as herbicides | Bayer CropScience AG (DE) | 2005-11-23 | — | — | EP | disclosed |
| EP-1206468-B1 | SUBSTITUTED THIENYL(AMINO)SULFONYLUREAS | BAYER CROPSCIENCE AG (DE) | 2005-06-15 | — | — | EP | disclosed |
| EP-1200426-B1 | SUBSTITUTED THIENE-3-YL-SULFONYL AMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | BAYER CROPSCIENCE AG (DE) | 2004-02-25 | — | — | EP | disclosed |
| EP-1206468-A2 | SUBSTITUTED THIENYL(AMINO)SULFONYLUREAS | Bayer Aktiengesellschaft (DE) | 2002-05-22 | — | — | EP | disclosed |
| EP-1200426-A1 | SUBSTITUTED THIENE-3-YL-SULFONYL AMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | Bayer Aktiengesellschaft (DE) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001010863-A2 | SUBSTITUTED THIENYL(AMINO)SULFONYLUREAS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-15 | — | — | WO | disclosed |
| WO-2001005788-A1 | SUBSTITUTED THIENE-3-YL-SULFONYL AMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-25 | — | — | WO | disclosed |
| WO-1997028166-A1 | THIENOQUINOLINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1997-08-07 | — | — | WO | disclosed |