Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | THPO | P40225 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29362308 | 0.88 | ALDH1A1 (0.52) | EGFRERBB2ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL2967462 | 0.88 | ALDH1A1 (0.52) | EGFRERBB2ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL30537036 | 0.86 | EGFR (0.49) | EGFRERBB2ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL2117010 | 0.82 | EGFR (0.49) | EGFRERBB2ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL15326052 | 0.74 | ALDH1A1 (0.50) | ALDH1A1CYP3A4SMN1; SMN2LMNAMAPT | |
| SCHEMBL10442604 | 0.74 | EGFR (0.56) | EGFRERBB2ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL9978465 | 0.73 | EGFR (0.45) | EGFRERBB2ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL17508143 | 0.73 | KCNQ2 (0.44) | ALDH1A1LMNATDP1HDAC6HDAC1 | |
| SCHEMBL16820449 | 0.72 | LMNA (0.56) | ALDH1A1SMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL6410341 | 0.72 | LMNA (0.56) | ALDH1A1SMN1; SMN2LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |
| WO-1994003434-A1 | IMIDAZOLE-CONTAINING ANALOGS OF DISTAMYCIN | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-02-17 | — | — | WO | disclosed |
| US-5273991-A | Anticarcinogenic agents | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-12-28 | — | — | US | disclosed |