Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.49 |
| ▸ | ITGAV | P06756 | 12/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.38 |
| ▸ | JAK3 | P52333 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382345 | 0.93 | ITGB3 (0.55) | ITGB3ITGAVITGA2BALDH1A1USP2 | |
| SCHEMBL7461788 | 0.92 | ITGB3 (0.56) | ITGB3ITGAVITGA2B | |
| SCHEMBL7473372 | 0.87 | ITGB3 (0.46) | ITGB3ITGAVITGA2BALDH1A1USP2 | |
| SCHEMBL382306 | 0.85 | ITGB3 (0.65) | ITGB3ITGAVITGA2B | |
| SCHEMBL7467585 | 0.84 | ITGB3 (0.65) | ITGB3ITGAVITGA2B | |
| SCHEMBL7462044 | 0.84 | ITGB3 (0.65) | ITGB3ITGAVITGA2B | |
| SCHEMBL7463165 | 0.83 | ITGB3 (0.65) | ITGB3ITGAVITGA2B | |
| SCHEMBL382475 | 0.82 | ITGB3 (0.43) | ITGB3ITGAVITGA2BALDH1A1SMN1; SMN2 | |
| SCHEMBL7467234 | 0.80 | ITGB3 (0.74) | ITGB3ITGAVITGA2B | |
| SCHEMBL7461811 | 0.79 | ITGB3 (0.52) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |