Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GGT1 | P19440 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27768002 | 0.80 | KMT2A (0.36) | ALDH1A1MAPK1CYP1A2 | |
| SCHEMBL10872973 | 0.78 | KDM4E (0.41) | CFDKDM4ETSHRHSD17B10ALDH1A1 | |
| SCHEMBL27653353 | 0.76 | KDM4E (0.40) | CFDKDM4ETSHRHSD17B10ALDH1A1 | |
| SCHEMBL28742962 | 0.76 | ALDH1A1 (0.44) | CFDKDM4ETSHRHSD17B10ALDH1A1 | |
| SCHEMBL11808741 | 0.74 | RAB9A (0.42) | CFDKDM4ETSHRHSD17B10ALDH1A1 | |
| SCHEMBL1162160 | 0.74 | RAB9A (0.48) | CFDKDM4ETSHRHSD17B10ALDH1A1 | |
| SCHEMBL12874104 | 0.73 | KMT2A (0.40) | CFDKDM4ETSHRHSD17B10ALDH1A1 | |
| SCHEMBL27703251 | 0.72 | POLB (0.39) | CFDKDM4ETSHRHSD17B10ALDH1A1 | |
| SCHEMBL11463026 | 0.72 | KMT2A (0.63) | KDM4EALDH1A1HPGDLMNACYP1A2 | |
| SCHEMBL9297516 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102812016-B | Organic electronic devices and polymers including photovoltaic cells and diketone-based polymers | SOLVAY USA INC. (US) | 2015-12-09 | — | — | CN | disclosed |
| CN-101528704-B | Serine-threonine protein kinase and PARP modulators | CYLENE PHARMACEUTICALS INC | 2014-04-09 | — | — | CN | disclosed |
| CN-102812016-A | Organic electronic devices and polymers including photovoltaic cells and diketone-based polymers | PLEXTRONICS INC | 2012-12-05 | — | — | CN | disclosed |
| CN-101528704-A | Serine-threonine protein kinase and PARP modulators | CYLENE PHARMACEUTICALS INC (US) | 2009-09-09 | — | — | CN | disclosed |
| EP-1077701-A4 | ANTI-VIRAL COMPOUNDS | LILLY CO ELI (US) | 2002-03-20 | — | — | EP | disclosed |
| CN-1292697-A | Anti-viral compound | LILLY CO ELI (US) | 2001-04-25 | — | — | CN | disclosed |
| EP-1077701-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-02-28 | — | — | EP | disclosed |
| CN-1053904-C | Novel N-pyridyl carboxamides and derivatives, processes for their preparation and the pharmaceutical compositions which contain them | ADIR (FR) | 2000-06-28 | — | — | CN | disclosed |
| WO-1999059587-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-11-25 | — | — | WO | disclosed |
| CN-1121074-A | Novel N-pyridyl carboxamides and derivatives, processes for their preparation and the pharmaceutical compositions which contain them | ADIR (FR) | 1996-04-24 | — | — | CN | disclosed |