SCHEMBL7473546

SCHEMBL7473546

CCCCCCCCCCCCCCCCCCNC(=O)N1CCCCC1CCON(C=O)CCCN(CCO)CCO

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 3/20 0.33
NPSR1 Q6W5P4 1/20 0.33
NAAA Q02083 1/20 0.33
OPRD1 P41143 1/20 0.32
MEN1 O00255 1/20 0.32
GALR3 O60755 1/20 0.32
KMT2A Q03164 1/20 0.32
EPHX1 P07099 7/20 0.32
EPHX2 P34913 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7479745 0.91 DPP4 (0.34) DPP4NPSR1NAAAOPRD1EPHX1
SCHEMBL7472660 0.90 DPP4 (0.35) DPP4NPSR1NAAAOPRD1EPHX1
Hydrochloric Acid SCHEMBL7478947 0.89 DPP4 (0.34) DPP4NPSR1NAAAOPRD1EPHX1
SCHEMBL7473775 0.88 DNM1 (0.37) DPP4NPSR1NAAAOPRD1
SCHEMBL7479938 0.87 MEN1 (0.38) DPP4NPSR1NAAAMEN1KMT2A
SCHEMBL7471608 0.87 KDM4E (0.39) OPRD1
SCHEMBL7484144 0.86 KDM4E (0.41) DPP4NPSR1NAAAOPRD1
SCHEMBL8299995 0.86 MEN1 (0.34) MEN1GALR3KMT2A
SCHEMBL7481147 0.86 HRH3 (0.42) EPHX2
SCHEMBL7482931 0.85 DPP4 (0.33) DPP4NPSR1NAAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0933361-B1 1,2-Di-substituted piperidine derivatives as hair growth promoter SHISEIDO CO LTD (JP) 2002-03-27 EP disclosed
US-6057337-A USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS SHISEIDO CO., LTD. (JP) 2000-05-02 US disclosed
EP-0933361-A1 1,2-Di-substituted piperidine derivatives as hair growth promoter SHISEIDO COMPANY LIMITED (JP) 1999-08-04 EP disclosed