Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FPR3 | P25089 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471608 | 0.95 | KDM4E (0.39) | KDM4EGNAI3GNAO1GNAI1HRH3 | |
| SCHEMBL7477978 | 0.94 | GNAI3 (0.36) | KDM4EGNAI3GNAO1GNAI1HRH3 | |
| Hydrochloric Acid SCHEMBL7474248 | 0.93 | GNAO1 (0.38) | KDM4EGNAI3GNAO1GNAI1HRH3 | |
| SCHEMBL8175563 | 0.90 | GNAI3 (0.38) | KDM4EGNAI3GNAO1GNAI1HRH3 | |
| SCHEMBL7479938 | 0.90 | MEN1 (0.38) | GNAI3GNAO1GNAI1MAPTTP53 | |
| SCHEMBL7474633 | 0.90 | MAPT (0.45) | KDM4EGNAI3GNAO1GNAI1MAPT | |
| SCHEMBL7472660 | 0.89 | DPP4 (0.35) | OPRD1DPP4NPSR1NAAA | |
| Hydrochloric Acid SCHEMBL7472629 | 0.89 | MAPT (0.44) | KDM4EGNAI3GNAO1GNAI1MAPT | |
| Hydrochloric Acid SCHEMBL7478947 | 0.88 | DPP4 (0.34) | GNAI3GNAO1GNAI1OPRD1DPP4 | |
| SCHEMBL7479745 | 0.88 | DPP4 (0.34) | OPRD1DPP4NPSR1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |