Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 5/20 | 0.61 |
| ▸ | GSTM2 | P28161 | 5/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11973051 | 0.88 | POLB (0.72) | GSTP1GSTM2POLBCYP1A2CYP3A4 | |
| SCHEMBL2960962 | 0.83 | MAPT (0.69) | GSTP1GSTM2POLBMAPTHTT | |
| SCHEMBL260444 | 0.82 | KMT2A (0.62) | GSTP1GSTM2POLBHPGDMAPT | |
| SCHEMBL5913906 | 0.82 | ALDH1A1 (0.60) | POLBHPGDMAPTKMT2AALDH1A1 | |
| SCHEMBL30902227 | 0.81 | SMN1; SMN2 (0.49) | GSTP1GSTM2MAPTHTTKMT2A | |
| SCHEMBL7473558 | 0.80 | KMT2A (0.56) | POLBMAPTKMT2AALDH1A1RAB9A | |
| SCHEMBL2925221 | 0.80 | GSTP1 (0.53) | GSTP1GSTM2POLBCYP1A2CYP3A4 | |
| SCHEMBL4004627 | 0.79 | KMT2A (0.58) | GSTP1GSTM2POLBHPGDMAPT | |
| SCHEMBL4671094 | 0.79 | ALDH1A1 (0.54) | GSTP1GSTM2POLBMAPTHTT | |
| SCHEMBL5299658 | 0.78 | ABCB1 (0.55) | POLBMAPTKMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636622-B1 | Isoxazole derivatives and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-23 | — | — | EP | disclosed |
| EP-1160244-A1 | Isoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LIMITED (GB) | 2001-12-05 | — | — | EP | disclosed |
| US-5489570-A | PRE- OR POST-EMERGENCE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-02-06 | — | — | US | disclosed |
| EP-0636622-A1 | Isoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-02-01 | — | — | EP | disclosed |