Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1304734 | 0.83 | KMT2A (0.60) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL4002932 | 0.82 | ALDH1A1 (0.55) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL3127542 | 0.82 | KMT2A (0.61) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL4262486 | 0.82 | KMT2A (0.61) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL28066675 | 0.81 | KMT2A (0.57) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL6704626 | 0.81 | KMT2A (0.60) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL7052691 | 0.81 | LMNA (0.64) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL310490 | 0.81 | KMT2A (0.60) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL3841850 | 0.81 | KMT2A (0.63) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL5299658 | 0.81 | ABCB1 (0.55) | KMT2AALDH1A1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636622-B1 | Isoxazole derivatives and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-23 | — | — | EP | disclosed |
| EP-1160244-A1 | Isoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LIMITED (GB) | 2001-12-05 | — | — | EP | disclosed |
| US-5489570-A | PRE- OR POST-EMERGENCE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-02-06 | — | — | US | disclosed |
| EP-0636622-A1 | Isoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-02-01 | — | — | EP | disclosed |