Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206856 | 0.90 | KDM4E (0.43) | KMT2ACHRM2DRD2DRD4DRD3 | |
| SCHEMBL7207516 | 0.88 | ADRA1D (0.46) | KMT2ADRD2DRD4DRD3 | |
| SCHEMBL7207966 | 0.88 | KMT2A (0.51) | KMT2ADRD2DRD4DRD3 | |
| SCHEMBL7483876 | 0.86 | KMT2A (0.45) | KMT2ADRD2DRD4DRD3 | |
| SCHEMBL7482639 | 0.79 | KMT2A (0.42) | KMT2ADRD2DRD4DRD3 | |
| SCHEMBL7207584 | 0.77 | DRD2 (0.47) | DRD2DRD4DRD3 | |
| SCHEMBL7211786 | 0.72 | KMT2A (0.50) | KMT2ADRD2DRD4DRD3 | |
| SCHEMBL7478885 | 0.71 | DRD2 (0.54) | DRD2DRD4DRD3 | |
| SCHEMBL8617146 | 0.71 | PPARG (0.34) | — | |
| SCHEMBL7207549 | 0.68 | DRD4 (0.64) | KMT2ADRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923551-B1 | 4-AMINOETHOXY INDOLONE DERIVATIVES | AMERICAN HOME PROD (US) | 2002-06-05 | — | — | EP | disclosed |
| EP-0923551-A1 | 4-AMINOETHOXY INDOLONE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008819-A1 | 4-AMINOETHOXY INDOLONE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-03-05 | — | — | WO | disclosed |