Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7382333 | 1.00 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2L3MBTL1MAPK1SLC6A2 | |
| Glycolic Acid SCHEMBL1813600 | 0.95 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2L3MBTL1MAPK1SLC6A2 | |
| SCHEMBL11662689 | 0.85 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2L3MBTL1MAPK1SLC6A2 | |
| SCHEMBL9219335 | 0.83 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2L3MBTL1MAPK1SLC6A2 | |
| SCHEMBL5421388 | 0.83 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2L3MBTL1MAPK1SLC6A2 | |
| SCHEMBL31422729 | 0.83 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2L3MBTL1MAPK1SLC6A2 | |
| SCHEMBL2957718 | 0.82 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2L3MBTL1MAPK1SLC6A2 | |
| SCHEMBL5146905 | 0.82 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2L3MBTL1MAPK1SLC6A2 | |
| Carbamic Acid SCHEMBL28819973 | 0.82 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2L3MBTL1MAPK1SLC6A2 | |
| SCHEMBL8043863 | 0.81 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2L3MBTL1MAPK1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950046-B1 | 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS | NAEJA PHARMACEUTICAL INC (CA) | 2002-04-10 | — | — | EP | claimed |