Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL16991767 | 0.91 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2ABCB1 | |
| Carbamic Acid SCHEMBL16991750 | 0.91 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2ABCB1 | |
| Carbamic Acid SCHEMBL28540227 | 0.87 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2ALOX5MAPK1L3MBTL1 | |
| SCHEMBL31422729 | 0.82 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL5421388 | 0.82 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL7382333 | 0.82 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL7473612 | 0.82 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL28661362 | 0.82 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2SLC6A2SLC6A3KMT2A | |
| Glycolic Acid SCHEMBL1813600 | 0.80 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL19357462 | 0.79 | ABCB1 (0.52) | ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114917361-A | Antibody Drug Conjugates (ADC) and antibody prodrug conjugates (APDC) with enzyme cleavable groups | 拜耳医药股份有限公司 | 2022-08-19 | — | — | CN | disclosed |