Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680083 | 0.79 | ENPP2 (0.45) | MMP3ENPP2ALDH1A1TAAR1FFAR4 | |
| SCHEMBL101334 | 0.74 | TAAR1 (0.55) | ENPP2TAAR1 | |
| SCHEMBL8506181 | 0.73 | ENPP2 (0.45) | MMP3ENPP2TAAR1FFAR1FFAR4 | |
| SCHEMBL5176295 | 0.73 | MEP1B (0.47) | MMP3ENPP2FFAR1FFAR4HCRTR1 | |
| SCHEMBL8784075 | 0.69 | TAAR1 (0.49) | ENPP2ALDH1A1TAAR1 | |
| SCHEMBL2294721 | 0.68 | TP53 (0.50) | MMP3ENPP2ALDH1A1 | |
| SCHEMBL30245956 | 0.68 | KDM4E (0.47) | MMP3ENPP2ALDH1A1 | |
| SCHEMBL29194698 | 0.68 | KDM4E (0.47) | MMP3ENPP2ALDH1A1 | |
| SCHEMBL7265579 | 0.68 | PRMT5 (0.43) | MMP3ENPP2ALDH1A1TAAR1 | |
| SCHEMBL10545623 | 0.68 | SMN1; SMN2 (0.56) | ENPP2ALDH1A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636025-A4 | COMPOUNDS USEFUL FOR TREATING ALLERGIC OR INFLAMMATORY DISEASES. | — | 1995-02-22 | — | — | EP | disclosed |
| EP-0636025-A1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC OR INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-02-01 | — | — | EP | disclosed |
| WO-1993019750-A1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC OR INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-10-14 | — | — | WO | disclosed |