Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253142 | 0.86 | NPC1 (0.34) | NPC1RAB9AMAPTALDH1A1HTT | |
| SCHEMBL7480242 | 0.80 | NPC1 (0.35) | NPC1RAB9AMAPTALDH1A1HTT | |
| SCHEMBL7479723 | 0.80 | NPC1 (0.35) | NPC1RAB9AMAPTALDH1A1HTT | |
| SCHEMBL5705240 | 0.75 | NPC1 (0.39) | NPC1RAB9AMAPTALDH1A1HTT | |
| SCHEMBL7476971 | 0.74 | ABCB1 (0.50) | CYP3A4ABCB1 | |
| SCHEMBL668764 | 0.74 | ABCB1 (0.57) | HTTCYP3A4CYP2C9CYP2C19ABCB1 | |
| SCHEMBL7472544 | 0.70 | ABCB1 (0.39) | NPC1RAB9AMAPTALDH1A1CYP3A4 | |
| SCHEMBL9903289 | 0.70 | NPC1 (0.35) | NPC1RAB9AMAPTALDH1A1HTT | |
| SCHEMBL7479127 | 0.69 | ABCB1 (0.39) | NPC1RAB9AMAPTALDH1A1ABCB1 | |
| SCHEMBL19946456 | 0.69 | HSD17B10 (0.36) | NPC1RAB9AMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496342-B2 | New hydrazine derivative and pesticidal composition comprising said derivative as an effective ingredient | NIPPON KAYAKU KK (JP) | 2002-07-24 | — | — | EP | claimed |
| EP-0496342-B2 | New hydrazine derivative and pesticidal composition comprising said derivative as an effective ingredient | NIPPON KAYAKU KK (JP) | 2002-07-24 | — | — | EP | disclosed |
| US-5378726-A | Insecticide, parasiticide | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1995-01-03 | — | — | US | disclosed |