Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2683389 | 0.94 | TAS1R3 (0.37) | ALDH1A1MAPTHPGDTAS1R3TAS1R1 | |
| SCHEMBL9903289 | 0.93 | NPC1 (0.35) | NPC1RAB9AALDH1A1MAPTNPSR1 | |
| SCHEMBL19946432 | 0.91 | ABCB1 (0.34) | HSD17B10NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL9101336 | 0.83 | ABCB1 (0.35) | HSD17B10NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL5705240 | 0.81 | NPC1 (0.39) | NPC1RAB9AALDH1A1MAPTHTT | |
| SCHEMBL29684859 | 0.79 | ABCB1 (0.36) | NPC1RAB9AALDH1A1MAPTHPGD | |
| SCHEMBL668634 | 0.79 | ABCB1 (0.36) | NPC1RAB9AALDH1A1MAPTHPGD | |
| SCHEMBL2683648 | 0.79 | ABCB1 (0.36) | NPC1RAB9AALDH1A1MAPTHPGD | |
| SCHEMBL9903268 | 0.79 | ALDH1A1 (0.38) | HSD17B10NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL18625531 | 0.78 | ABCB1 (0.50) | TAS1R3TAS1R1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167458-B1 | CHIRAL DIACYLHYDRAZINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX | INTREXON CORP (US) | 2018-03-14 | — | — | EP | disclosed |