SCHEMBL7473797

SCHEMBL7473797

CC1(C)CC(OC(=O)CCCCCCCCC(=O)OC2CC(C)(C)N(OC3CC=CCC3)C(C)(C)C2)CC(C)(C)N1OC1CC=CCC1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.39
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
GAA P10253 1/20 0.38
ALDH1A1 P00352 2/20 0.36
USP2 O75604 1/20 0.36
ALOX15 P16050 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TSHR P16473 2/20 0.33
ESR1 P03372 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30894533 0.84 NAAA (0.55) NAAASMN1; SMN2KMT2AMEN1GAA
SCHEMBL9743615 0.83 NAAA (0.56) NAAASMN1; SMN2KMT2AMEN1GAA
SCHEMBL30894534 0.83 NAAA (0.56) NAAASMN1; SMN2KMT2AMEN1GAA
SCHEMBL698203 0.83 NAAA (0.56) NAAASMN1; SMN2KMT2AMEN1GAA
SCHEMBL10467609 0.83 NAAA (0.56) NAAASMN1; SMN2KMT2AMEN1GAA
SCHEMBL453206 0.82 NAAA (0.54) NAAASMN1; SMN2KMT2AMEN1GAA
SCHEMBL7478396 0.80 NAAA (0.44) NAAASMN1; SMN2KMT2AMEN1GAA
SCHEMBL1938967 0.79 NAAA (0.51) NAAASMN1; SMN2KMT2AMEN1GAA
SCHEMBL1232050 0.79 NAAA (0.66) NAAASMN1; SMN2KMT2AMEN1GAA
SCHEMBL20194432 0.79 NAAA (0.66) NAAASMN1; SMN2KMT2AMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0309402-B2 N-substituted hindered amine stabilizers CIBA SC HOLDING AG (CH) 2002-06-12 EP disclosed
EP-0309402-B1 N-substituted hindered amine stabilizers CIBA GEIGY AG (CH) 1995-01-11 EP disclosed
EP-0309402-A1 N-substituted hindered amine stabilizers CIBA-GEIGY AG (CH) 1989-03-29 EP disclosed