Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.37 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473975 | 0.74 | IDO1 (0.48) | AHRPDE7ACYP19A1MEN1KMT2A | |
| SCHEMBL6221451 | 0.72 | AHR (0.54) | AHRPDE7APDE7BNSD2BCHE | |
| SCHEMBL3201760 | 0.66 | CYP19A1 (0.48) | CYP19A1 | |
| SCHEMBL10365303 | 0.65 | AHR (0.45) | AHRPDE7APDE7BAKR1B1NSD2 | |
| SCHEMBL11729336 | 0.64 | PDE7A (0.43) | AHRPDE7APDE7BKMT2ANSD2 | |
| SCHEMBL28102818 | 0.61 | CNR2 (0.36) | MEN1KMT2ANSD2BCHEDAO | |
| SCHEMBL21257765 | 0.61 | AHR (0.60) | AHRPDE7APDE7BKMT2ANSD2 | |
| SCHEMBL2269040 | 0.60 | PDK2 (0.61) | AHRPDE7APDE7BNSD2BCHE | |
| SCHEMBL12290765 | 0.60 | AKR1B1 (0.38) | PDE7AMEN1KMT2AAKR1B1CES1 | |
| SCHEMBL29860150 | 0.59 | PDE7A (0.51) | AHRPDE7APDE7BNSD2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697405-B1 | Substituted quinoline derivatives, process for their preparation and their use | AVENTIS PHARMA GMBH (DE) | 2002-08-14 | — | — | EP | disclosed |
| EP-0697405-A1 | Substituted quinoline derivatives, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-02-21 | — | — | EP | disclosed |