Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | CBX7 | O95931 | 2/20 | 0.41 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.41 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.41 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.41 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.40 |
| ▸ | AHR | P35869 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696406 | 0.74 | IDO1 (0.51) | IDO1CBX7CDYLCDYL2CDY1; CDY1B | |
| SCHEMBL7473979 | 0.74 | AHR (0.40) | AHRMEN1KMT2APDE7AAKR1B1 | |
| SCHEMBL19260231 | 0.72 | AHR (0.54) | IDO1CYP46A1AHRMEN1KMT2A | |
| SCHEMBL7650332 | 0.71 | CYP46A1 (0.47) | CYP46A1 | |
| SCHEMBL9539898 | 0.69 | PDE7A (0.47) | IDO1MEN1KMT2AHTR7PDE7A | |
| SCHEMBL28336703 | 0.68 | AKR1A1 (0.39) | IDO1CBX7CDYLCDYL2CDY1; CDY1B | |
| SCHEMBL30452208 | 0.67 | MAP3K14 (0.37) | IDO1MEN1KMT2AAKR1B1 | |
| SCHEMBL7704788 | 0.66 | CYP46A1 (0.60) | CYP46A1 | |
| SCHEMBL8786069 | 0.66 | PGR (0.44) | IDO1CYP46A1AHRCMA1HTR7 | |
| SCHEMBL3201760 | 0.66 | CYP19A1 (0.48) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697405-B1 | Substituted quinoline derivatives, process for their preparation and their use | AVENTIS PHARMA GMBH (DE) | 2002-08-14 | — | — | EP | disclosed |
| EP-0697405-A1 | Substituted quinoline derivatives, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-02-21 | — | — | EP | disclosed |