Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.60 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.60 |
| ▸ | XIAP | P98170 | 14/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-692585 SCHEMBL9025213 | 1.00 | GHSR (0.60) | GHSRAGTR1XIAP | |
| L-692585 SCHEMBL9024978 | 1.00 | GHSR (0.60) | GHSRAGTR1XIAP | |
| SCHEMBL9025440 | 0.95 | GHSR (0.61) | GHSRAGTR1XIAP | |
| SCHEMBL9025740 | 0.95 | GHSR (0.59) | GHSRAGTR1XIAP | |
| SCHEMBL9025110 | 0.95 | GHSR (0.59) | GHSRAGTR1XIAP | |
| SCHEMBL9024918 | 0.95 | GHSR (0.59) | GHSRAGTR1XIAP | |
| SCHEMBL9025241 | 0.94 | GHSR (0.60) | GHSRAGTR1XIAP | |
| SCHEMBL9024619 | 0.94 | GHSR (0.60) | GHSRAGTR1XIAP | |
| SCHEMBL9024677 | 0.94 | GHSR (0.60) | GHSRAGTR1XIAP | |
| SCHEMBL9024596 | 0.94 | GHSR (0.53) | GHSRAGTR1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513974-B1 | Novel benzo-fused lactams that promote the release of growth hormone | MERCK & CO INC (US) | 1996-09-04 | — | — | EP | claimed |
| EP-0513974-A1 | Novel benzo-fused lactams that promote the release of growth hormone | MERCK & CO. INC. (US) | 1992-11-19 | — | — | EP | claimed |
| WO-1992016524-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1992-10-01 | — | — | WO | claimed |
| EP-1159964-B1 | Use of growth hormone secretagogues for stimulating gastrointestinal motility | PFIZER PROD INC (US) | 2009-10-28 | — | — | EP | disclosed |
| US-20080051403-A1 | Treatment For Alzheimer's Disease And Related Conditions | PINEIRO JOSE LUIS CASTRO | 2008-02-28 | — | — | US | disclosed |
| WO-2005027913-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS COMPRISING COMBINATIONS OF 2-ALKYLIDENE-19-NOR-VITAMIN D DERIVATIVES AND A GROWTH HORMONE SECRETAGOGUE | PFIZER PRODUCTS INC. (US) | 2005-03-31 | — | — | WO | disclosed |
| WO-2004108120-A1 | USE OF GROWTH HORMONE SECRETAGOGUES FOR TREATMENT OF FIBROMYALGIA | PFIZER PRODUCTS INC. (US) | 2004-12-16 | — | — | WO | disclosed |
| EP-0513974-B1 | Novel benzo-fused lactams that promote the release of growth hormone | MERCK & CO INC (US) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995011029-A1 | COMBINATION OF BISPHOSPHONATES AND GROWTH HORMONE SECRETAGOGUES | MERCK & CO., INC. (US) | 1995-04-27 | — | — | WO | disclosed |
| US-5310737-A | Benzo-fused lactams that promote the release of growth hormone | MERCK & CO., INC. (US) | 1994-05-10 | — | — | US | disclosed |
| US-5206235-A | Animal growth regulators; stimulants | MERCK & CO., INC. (US) | 1993-04-27 | — | — | US | disclosed |
| EP-0513974-A1 | Novel benzo-fused lactams that promote the release of growth hormone | MERCK & CO. INC. (US) | 1992-11-19 | — | — | EP | disclosed |
| WO-1992016524-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1992-10-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051403-A1 | Treatment For Alzheimer's Disease And Related Conditions | GHSR, APP, BDNF | GHSR 1/4885AGTR1 401/4885XIAP 2168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.