Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5983869 | 0.88 | KDM4E (0.50) | HTTALOX15KDM4ECA12CA1 | |
| SCHEMBL3649032 | 0.84 | CA12 (0.48) | HTTKDM4ECA12CA1CA2 | |
| SCHEMBL3648771 | 0.82 | ACSS2 (0.49) | ACSS2SMN1; SMN2TDP1 | |
| SCHEMBL3651101 | 0.79 | ACSS2 (0.42) | ACSS2LMNAHPGDGAASMN1; SMN2 | |
| SCHEMBL2881811 | 0.74 | KDM4E (0.51) | HTTALOX15KDM4ECA12CA1 | |
| SCHEMBL29555125 | 0.74 | FGFR1 (0.53) | HTTALOX15KDM4ECA12CA1 | |
| SCHEMBL2884485 | 0.74 | HCAR3 (0.53) | HTTALOX15KDM4ECA12CA1 | |
| SCHEMBL3492748 | 0.74 | FGFR1 (0.53) | HTTALOX15KDM4ECA12CA1 | |
| SCHEMBL31721245 | 0.73 | HTT (0.49) | HTTALOX15KDM4ECA12CA1 | |
| SCHEMBL3596405 | 0.73 | NPC1 (0.61) | HTTALOX15KDM4ECA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026933-A1 | SUBSTITUTED AMIDINOARYL DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |