Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 12/20 | 0.46 |
| ▸ | MEN1 | O00255 | 11/20 | 0.46 |
| ▸ | RAB9A | P51151 | 10/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | NPC1 | O15118 | 8/20 | 0.46 |
| ▸ | HPGD | P15428 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6850196 | 0.79 | KDM4E (0.45) | KMT2AMEN1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8148244 | 0.79 | MEN1 (0.42) | KMT2AMEN1RAB9AKDM4EALDH1A1 | |
| SCHEMBL6855899 | 0.79 | KDM4E (0.65) | KMT2AMEN1RAB9AKDM4EALDH1A1 | |
| SCHEMBL3946877 | 0.78 | KMT2A (0.50) | KMT2AMEN1RAB9AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8150702 | 0.77 | KMT2A (0.49) | KMT2AMEN1RAB9AKDM4EALDH1A1 | |
| SCHEMBL6856405 | 0.76 | POLB (0.48) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL11603518 | 0.76 | KDM4E (0.54) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL6855708 | 0.73 | ALDH1A1 (0.50) | KMT2AMEN1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7443932 | 0.70 | KMT2A (0.51) | KMT2AMEN1RAB9AKDM4EALDH1A1 | |
| SCHEMBL10164304 | 0.66 | ALDH1A1 (0.47) | KMT2AMEN1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0847271-B1 | PYRAZOLO-(1,5-a)-PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND HAIR DYES CONTAINING THESE | OREAL (FR) | 2002-05-02 | — | — | EP | disclosed |
| US-6099593-A | (DI)AMINO-SUBSTITUTED PYRAZOLO(1,5-A)PYRIMIDINES AS OXIDATION BASE; PRODUCE INTENSE COLORATIONS AND WHICH HAVE GOOD RESISTANCE TO EXTERNAL AGENTS SUCH AS LIGHT, WEATHER, WASHING, ARE READILY SYNTHESIZABLE AND ARE CHEMICALLY STABLE | L'OREAL (FR) | 2000-08-08 | — | — | US | disclosed |
| EP-0847271-A1 | PYRAZOLO-(1,5-a)-PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND HAIR DYES CONTAINING THESE | L'OREAL (FR) | 1998-06-17 | — | — | EP | disclosed |
| WO-1997049378-A1 | PYRAZOLO-(1,5-a)-PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND HAIR DYES CONTAINING THESE | L'OREAL (FR) | 1997-12-31 | — | — | WO | disclosed |