Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GPR39 | O43194 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474520 | 0.79 | KMT2A (0.46) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL3947238 | 0.78 | PDE2A (0.51) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL6856405 | 0.77 | POLB (0.48) | MEN1KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL11603518 | 0.77 | KDM4E (0.54) | MEN1KMT2APOLBL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8150701 | 0.76 | PDE2A (0.50) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL6855708 | 0.74 | ALDH1A1 (0.50) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL6855899 | 0.69 | KDM4E (0.65) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL26253848 | 0.69 | PKM (0.42) | MEN1KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL10164304 | 0.67 | ALDH1A1 (0.47) | MEN1KMT2APOLBL3MBTL1ALDH1A1 | |
| SCHEMBL23327762 | 0.66 | CDK2 (0.38) | MEN1KMT2APOLBL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6099593-A | (DI)AMINO-SUBSTITUTED PYRAZOLO(1,5-A)PYRIMIDINES AS OXIDATION BASE; PRODUCE INTENSE COLORATIONS AND WHICH HAVE GOOD RESISTANCE TO EXTERNAL AGENTS SUCH AS LIGHT, WEATHER, WASHING, ARE READILY SYNTHESIZABLE AND ARE CHEMICALLY STABLE | L'OREAL (FR) | 2000-08-08 | — | — | US | disclosed |