Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7487974 | 0.91 | PTGS2 (0.42) | ALDH1A1KDM4ERAB9APTGS2CES2 | |
| SCHEMBL1376503 | 0.82 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL5101395 | 0.79 | PTGS2 (0.68) | PTGS2PTGS1 | |
| SCHEMBL5094209 | 0.70 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL5094165 | 0.68 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL7450024 | 0.67 | HTR2A (0.47) | ALDH1A1KDM4ERAB9APTGS2PTGS1 | |
| SCHEMBL1379215 | 0.66 | PTGS2 (0.54) | PTGS2PTGS1HSD11B1 | |
| SCHEMBL6901981 | 0.65 | PTGS2 (0.68) | ALDH1A1KDM4ERAB9APTGS2PTGS1 | |
| SCHEMBL7606499 | 0.62 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL1377386 | 0.62 | PTGS2 (0.56) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263751-A1 | 2-PHENYLPYRAN-4-ONE DERIVATIVES | Almirall Prodesfarma AG (CH) | 2002-12-11 | — | — | EP | claimed |
| WO-2001068633-A1 | 2-PHENYLPYRAN-4-ONE DERIVATIVES | ALMIRALL PRODESFARMA AG (CH) | 2001-09-20 | — | — | WO | claimed |