Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474599 | 0.91 | ALDH1A1 (0.44) | PTGS2PTGS1MAPTCES2CES1 | |
| SCHEMBL5094209 | 0.80 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL1376503 | 0.73 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL5101395 | 0.70 | PTGS2 (0.68) | PTGS2PTGS1 | |
| SCHEMBL1376798 | 0.67 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL1379215 | 0.67 | PTGS2 (0.54) | PTGS2PTGS1HSD11B1 | |
| SCHEMBL1377386 | 0.67 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL7482337 | 0.67 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL7606499 | 0.65 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL7556388 | 0.64 | PTGS2 (0.64) | PTGS2PTGS1ALDH1A1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263751-A1 | 2-PHENYLPYRAN-4-ONE DERIVATIVES | Almirall Prodesfarma AG (CH) | 2002-12-11 | — | — | EP | claimed |
| WO-2001068633-A1 | 2-PHENYLPYRAN-4-ONE DERIVATIVES | ALMIRALL PRODESFARMA AG (CH) | 2001-09-20 | — | — | WO | claimed |