Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 7/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP9 | P55211 | 1/20 | 0.38 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5848760 | 1.00 | BRS3 (0.41) | BRS3CAPN1CACNA1GCACNA1HCACNA1I | |
| SCHEMBL5849232 | 0.86 | PSMB5 (0.48) | BRS3CAPN1CACNA1GCACNA1HCACNA1I | |
| SCHEMBL5848152 | 0.83 | POLB (0.43) | POLBPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5848714 | 0.83 | POLB (0.43) | POLBPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5849886 | 0.80 | ALDH1A1 (0.45) | ACHEALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL5848330 | 0.80 | CAPN1 (0.43) | BRS3CAPN1CACNA1GCACNA1HCACNA1I | |
| SCHEMBL5848762 | 0.79 | BRS3 (0.44) | BRS3CACNA1GCACNA1HCACNA1IACHE | |
| SCHEMBL5848122 | 0.78 | CTSK (0.51) | CAPN1 | |
| SCHEMBL5848313 | 0.77 | CARM1 (0.44) | — | |
| SCHEMBL5849215 | 0.76 | CTSK (0.46) | BRS3CAPN1CACNA1GCACNA1HCACNA1I |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254898-A1 | BENZENE-FUSED HETEROCYCLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-11-06 | — | — | EP | disclosed |