Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MB | P02144 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471763 | 0.81 | ALDH1A1 (0.46) | MAPTALDH1A1KMT2ACA12CA1 | |
| SCHEMBL10766968 | 0.81 | ALDH1A1 (0.50) | HSD17B10NAPRTMAPTALDH1A1KMT2A | |
| SCHEMBL5250996 | 0.81 | ALDH1A1 (0.50) | HSD17B10NAPRTALDH1A1KMT2AMEN1 | |
| SCHEMBL8662132 | 0.79 | ALDH1A1 (0.41) | HSD17B10NAPRTMAPTALDH1A1KMT2A | |
| SCHEMBL5475468 | 0.79 | SMN1; SMN2 (0.44) | HSD17B10NAPRTALDH1A1KMT2AMEN1 | |
| SCHEMBL5487260 | 0.79 | HSP90AA1 (0.41) | HSD17B10NAPRTMAPTALDH1A1POLB | |
| SCHEMBL7474651 | 0.77 | MAPK1 (0.43) | HSD17B10MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL27592775 | 0.76 | NAMPT (0.36) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL4838369 | 0.75 | — | — | |
| SCHEMBL7471949 | 0.75 | HSD17B10 (0.42) | HSD17B10NAPRTALDH1A1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194417-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AG (DE) | 2002-04-10 | — | — | EP | claimed |
| WO-2000078733-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | claimed |