Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GGT1 | P19440 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474826 | 0.86 | ALDH1A1 (0.40) | HSD17B10TSHRKDM4EPTGS2NAPRT | |
| SCHEMBL7474651 | 0.85 | MAPK1 (0.43) | HSD17B10KDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL7474112 | 0.83 | L3MBTL1 (0.37) | HSD17B10TSHRKDM4ENAPRTALDH1A1 | |
| SCHEMBL10766968 | 0.75 | ALDH1A1 (0.50) | HSD17B10TSHRNAPRTALDH1A1HPGD | |
| SCHEMBL7474735 | 0.75 | HSD17B10 (0.41) | HSD17B10TSHRKDM4ENAPRTALDH1A1 | |
| SCHEMBL5250996 | 0.75 | ALDH1A1 (0.50) | HSD17B10TSHRKDM4ENAPRTALDH1A1 | |
| SCHEMBL1452054 | 0.75 | PTGS2 (0.47) | HSD17B10TSHRKDM4EPTGS2NAPRT | |
| SCHEMBL6176436 | 0.75 | PTGS2 (0.47) | HSD17B10TSHRKDM4EPTGS2NAPRT | |
| SCHEMBL5475468 | 0.74 | SMN1; SMN2 (0.44) | HSD17B10KDM4ENAPRTALDH1A1HPGD | |
| SCHEMBL9672920 | 0.74 | PTGS2 (0.46) | HSD17B10TSHRKDM4EPTGS2NAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194417-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AG (DE) | 2002-04-10 | — | — | EP | claimed |
| WO-2000078733-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | claimed |
| EP-1194417-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AG (DE) | 2002-04-10 | — | — | EP | disclosed |
| WO-2000078733-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | disclosed |