Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.72 |
| ▸ | ITGAV | P06756 | 17/20 | 0.72 |
| ▸ | ITGA2B | P08514 | 12/20 | 0.72 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6793124 | 0.90 | ITGB3 (0.71) | ITGB3ITGAVITGA2B | |
| SCHEMBL7464521 | 0.88 | ITGB3 (0.79) | ITGB3ITGAVITGA2B | |
| SCHEMBL27360378 | 0.86 | ITGB3 (0.65) | ITGB3ITGAVITGA2BADRB1HDAC1 | |
| SCHEMBL30856555 | 0.86 | ITGB3 (0.65) | ITGB3ITGAVITGA2BADRB1HDAC1 | |
| SCHEMBL7461038 | 0.84 | ITGB3 (0.77) | ITGB3ITGAVITGA2B | |
| SCHEMBL7461023 | 0.84 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL7052834 | 0.84 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL6797319 | 0.83 | ITGB3 (0.64) | ITGB3ITGAVITGA2B | |
| SCHEMBL7459047 | 0.83 | ITGB3 (0.53) | ITGB3ITGAVITGA2BHDAC1HDAC8 | |
| SCHEMBL7459959 | 0.82 | ITGB3 (0.76) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | claimed |
| EP-1227083-A1 | 3-AMINOPIPERIDINE DERIVATIVES AS INTEGRIN $g(a)v$g(b)3 ANTAGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |