Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.64 |
| ▸ | ITGAV | P06756 | 14/20 | 0.64 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.64 |
| ▸ | HPGDS | O60760 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6793124 | 0.91 | ITGB3 (0.71) | ITGB3ITGAVITGA2B | |
| SCHEMBL383017 | 0.85 | ITGB3 (0.70) | ITGB3ITGAVITGA2BHPGDS | |
| SCHEMBL7474768 | 0.83 | ITGB3 (0.72) | ITGB3ITGAVITGA2B | |
| SCHEMBL6797331 | 0.82 | ITGB3 (0.58) | ITGB3ITGAVITGA2BADRB3 | |
| SCHEMBL6793131 | 0.82 | ITGB3 (0.59) | ITGB3ITGAVITGA2BCASRADRB3 | |
| SCHEMBL6796225 | 0.81 | CASR (0.44) | ITGB3ITGAVITGA2BHPGDSCNR1 | |
| SCHEMBL6797761 | 0.81 | ITGB3 (0.65) | ITGB3ITGAVITGA2B | |
| SCHEMBL383018 | 0.79 | ITGB3 (0.59) | ITGB3ITGAVITGA2BCASR | |
| SCHEMBL30856555 | 0.79 | ITGB3 (0.65) | ITGB3ITGAVITGA2BADRB3 | |
| SCHEMBL27360378 | 0.79 | ITGB3 (0.65) | ITGB3ITGAVITGA2BADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6750219-B1 | HAVING INTEGRIN ALPHA V BETA 3 ANTAGONISTIC ACTIVITY, GP IIB/IIIA ANTAGONISTIC ACTIVITY, AND/OR HUMAN PLATELET AGGREGATION INHIBITORY ACTIVITY AND ALSO HAVING EXCELLENT WATER SOLUBILITY | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-06-15 | — | — | US | claimed |
| EP-1209152-A1 | OMEGA-AMINO-ALPHA-HYDROXYCARBOXYLIC ACID DERIVATIVES HAVING INTEGRIN ALPHA V BETA 3 ANTAGONISM | MEIJI SEIKA KAISHA LTD. (JP) | 2002-05-29 | — | — | EP | claimed |
| US-6750219-B1 | HAVING INTEGRIN ALPHA V BETA 3 ANTAGONISTIC ACTIVITY, GP IIB/IIIA ANTAGONISTIC ACTIVITY, AND/OR HUMAN PLATELET AGGREGATION INHIBITORY ACTIVITY AND ALSO HAVING EXCELLENT WATER SOLUBILITY | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-06-15 | — | — | US | disclosed |
| EP-1209152-A1 | OMEGA-AMINO-ALPHA-HYDROXYCARBOXYLIC ACID DERIVATIVES HAVING INTEGRIN ALPHA V BETA 3 ANTAGONISM | MEIJI SEIKA KAISHA LTD. (JP) | 2002-05-29 | — | — | EP | disclosed |