Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10631998 | 0.84 | SLC6A4 (0.90) | SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL10632291 | 0.83 | SLC6A4 (0.88) | SLC6A4SLC6A3 | |
| SCHEMBL7720831 | 0.80 | SLC6A4 (1.00) | SLC6A4SLC6A3 | |
| SCHEMBL7418255 | 0.79 | SIGMAR1 (0.71) | SLC6A4SLC6A3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL10635083 | 0.79 | SLC6A4 (0.77) | SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL8647649 | 0.79 | LMNA (0.83) | SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL8642037 | 0.79 | LMNA (0.78) | SLC6A4SLC6A3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL11074176 | 0.79 | SLC6A4 (0.97) | SLC6A4SLC6A3 | |
| SCHEMBL7411351 | 0.78 | SLC6A4 (0.64) | SLC6A4SLC6A3 | |
| SCHEMBL8645362 | 0.78 | LMNA (0.81) | SLC6A4SLC6A3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276035-A | Central nervous system disorders; Parkinson's disease; antidepressant and dopaminergic agent | NOVO NORDISK A/S (DK) | 1994-01-04 | — | — | US | disclosed |
| EP-0541617-A1 | 1,4-DISUBSTITUTED PIPERAZINES. | NOVO NORDISK AS (DK) | 1993-05-19 | — | — | EP | disclosed |
| WO-1992001679-A1 | 1,4-DISUBSTITUTED PIPERAZINES | NOVO NORDISK A/S (DK) | 1992-02-06 | — | — | WO | disclosed |