Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 8/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473397 | 0.85 | PDE5A (0.59) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL7459033 | 0.84 | MAPT (0.46) | KMT2AMAPTALDH1A1LMNAEGFR | |
| SCHEMBL7473037 | 0.84 | SRC (0.49) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL7469494 | 0.82 | PDE5A (0.46) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL7465985 | 0.82 | PDE5A (0.55) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL7467801 | 0.81 | EGFR (0.63) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL7468081 | 0.80 | KMT2A (0.42) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL7468592 | 0.80 | PDE5A (0.52) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL7466525 | 0.79 | MAPT (0.47) | KMT2AMEN1MAPTALDH1A1HTT | |
| SCHEMBL7469209 | 0.76 | KMT2A (0.51) | KMT2AMEN1MAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |