Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | PAK1 | Q13153 | 4/20 | 0.42 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463135 | 0.87 | CNR1 (0.53) | MAPTLMNAKDM4EALDH1A1PAK1 | |
| SCHEMBL7469209 | 0.86 | KMT2A (0.51) | MAPTLMNAHSD17B10KDM4ECYP1A2 | |
| SCHEMBL7469270 | 0.84 | KMT2A (0.49) | MAPTLMNACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL7466535 | 0.82 | CYP1A2 (0.38) | MAPTLMNAHSD17B10KDM4ECYP1A2 | |
| SCHEMBL7463150 | 0.80 | CYP1A2 (0.41) | MAPTHSD17B10KDM4ECYP1A2CYP2D6 | |
| SCHEMBL7464723 | 0.79 | PDGFRB (0.51) | MAPTPAK1 | |
| SCHEMBL7474860 | 0.79 | KMT2A (0.53) | MAPTLMNAHSD17B10KDM4ECYP1A2 | |
| SCHEMBL7468264 | 0.78 | PAK1 (0.48) | PAK1 | |
| SCHEMBL7473397 | 0.77 | PDE5A (0.59) | PDE5AALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7467225 | 0.77 | PAK1 (0.46) | MAPTLMNAALDH1A1PAK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |