Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.52 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 2/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.48 |
| ▸ | SRC | P12931 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7802761 | 0.83 | EGFR (0.72) | EGFRERBB2KDRABCG2 | |
| SCHEMBL7475093 | 0.83 | PDE5A (0.68) | MEN1ALDH1A1KMT2APDE5A | |
| SCHEMBL7474860 | 0.81 | KMT2A (0.53) | EGFRMAPTMEN1ALDH1A1HTT | |
| SCHEMBL1366535 | 0.81 | EGFR (0.68) | EGFRERBB2PDGFRBKDR | |
| SCHEMBL30294136 | 0.81 | EGFR (0.68) | EGFRERBB2PDGFRBKDR | |
| SCHEMBL7466349 | 0.80 | EGFR (0.67) | EGFRABCG2 | |
| SCHEMBL7461202 | 0.80 | PDE5A (0.53) | MEN1ALDH1A1KMT2APDE5A | |
| Hydrochloric Acid SCHEMBL8314953 | 0.80 | EGFR (0.67) | EGFRERBB2PDGFRBKDR | |
| SCHEMBL7474841 | 0.79 | PDE5A (0.48) | EGFRMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL8667642 | 0.78 | EGFR (0.66) | EGFRMAPTMEN1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |