Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7470602 | 0.85 | HPGD (0.42) | ALDH1A1LMNAAGTR1RAB9AMAPK1 | |
| SCHEMBL7474956 | 0.79 | S1PR4 (0.35) | ALDH1A1LMNAAGTR1RAB9AS1PR4 | |
| SCHEMBL7467478 | 0.78 | S1PR4 (0.41) | ALDH1A1LMNAHPGDCYP3A4CYP2C9 | |
| SCHEMBL28490932 | 0.75 | ALDH1A1 (0.76) | ALDH1A1LMNAAGTR1RAB9AMAPK1 | |
| SCHEMBL10679990 | 0.74 | MMP2 (0.55) | LMNATSHRL3MBTL1CA1CA2 | |
| SCHEMBL5708678 | 0.72 | MMP2 (0.53) | L3MBTL1 | |
| SCHEMBL7467822 | 0.71 | CA12 (0.48) | ALDH1A1MAPK1HPGDTSHRL3MBTL1 | |
| SCHEMBL1135982 | 0.71 | ALDH1A1 (0.66) | ALDH1A1LMNAAGTR1RAB9AMAPK1 | |
| SCHEMBL16065453 | 0.69 | ALDH1A1 (0.64) | ALDH1A1LMNAAGTR1RAB9AMAPK1 | |
| SCHEMBL4764067 | 0.69 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786457-B1 | AZOLE DERIVATIVES | YAMANOUCHI PHARMA CO LTD (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-5981559-A | USEFUL IN PREVENTING OR TREATING ALLERGIC DISEASES, ISCHEMIC HEART DISEASES OR ISCHEMIC BRAIN DISEASES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0786457-A1 | AZOLE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |