Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930684 | 0.88 | F2 (0.47) | F2KMT2AMEN1APOBEC3AAPOBEC3G | |
| SCHEMBL17232477 | 0.82 | L3MBTL1 (0.50) | F2KMT2AMEN1APOBEC3AAPOBEC3G | |
| SCHEMBL6926426 | 0.82 | F2 (0.45) | F2KMT2AMEN1APOBEC3AAPOBEC3G | |
| SCHEMBL1197438 | 0.82 | CRHBP (0.44) | F2KMT2AMEN1APOBEC3AAPOBEC3G | |
| SCHEMBL6931538 | 0.80 | KMT2A (0.48) | F2KMT2AMEN1APOBEC3AAPOBEC3G | |
| SCHEMBL14452034 | 0.78 | F2 (0.50) | F2KMT2AMEN1APOBEC3AAPOBEC3G | |
| SCHEMBL6930547 | 0.78 | F2 (0.42) | F2KMT2AMEN1APOBEC3AAPOBEC3G | |
| SCHEMBL17229307 | 0.78 | F2 (0.50) | F2KMT2AMEN1APOBEC3AAPOBEC3G | |
| SCHEMBL14438338 | 0.75 | F2 (0.52) | F2KMT2AMEN1APOBEC3AAPOBEC3G | |
| SCHEMBL17242393 | 0.73 | APOBEC3A (0.50) | KMT2AMEN1APOBEC3AAPOBEC3GCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002022584-A1 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2002-03-21 | — | — | WO | disclosed |