Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 6/20 | 0.68 |
| ▸ | PTGIR | P43119 | 11/20 | 0.67 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.67 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.64 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 4/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7840686 | 0.94 | PTGIR (0.74) | PTGER4PTGIRPTGER1PTGER3FABP4 | |
| SCHEMBL7477735 | 0.90 | PTGER4 (0.73) | PTGER4PTGIRPTGER1PTGER3PARP1 | |
| SCHEMBL7475495 | 0.90 | PTGER4 (0.78) | PTGER4PTGIRPTGER1PTGER3KDM4E | |
| SCHEMBL7844739 | 0.89 | PTGER4 (0.69) | PTGER4PTGIRPTGER1PTGER3KDM4E | |
| SCHEMBL7842424 | 0.87 | PTGER4 (0.64) | PTGER4PTGIRPTGER1PTGER3KDM4E | |
| SCHEMBL7476217 | 0.87 | PTGIR (0.79) | PTGER4PTGIRPTGER1PTGER3FABP4 | |
| SCHEMBL7493443 | 0.86 | PTGIR (0.71) | PTGER4PTGIRPTGER1PTGER3FABP4 | |
| SCHEMBL7486175 | 0.86 | PTGER4 (0.70) | PTGER4PTGIRPTGER1PTGER3MEN1 | |
| SCHEMBL7486168 | 0.86 | PTGER4 (0.70) | PTGER4PTGIRPTGER1PTGER3MEN1 | |
| Hydrochloric Acid SCHEMBL7481069 | 0.85 | PTGER4 (0.69) | PTGER4PTGIRPTGER1PTGER3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6437146-B1 | MESANGIAL PROLIFERATIVE GLOMERULONEPHRITIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-20 | — | — | US | disclosed |