Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.73 |
| ▸ | PTGIR | P43119 | 4/20 | 0.72 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.72 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.59 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475495 | 0.94 | PTGER4 (0.78) | PTGER4PTGIRPTGER1PTGER3PARP1 | |
| SCHEMBL7844739 | 0.91 | PTGER4 (0.69) | PTGER4PTGIRPTGER1PTGER3PARP1 | |
| SCHEMBL7475010 | 0.90 | PTGER4 (0.68) | PTGER4PTGIRPTGER1PTGER3PARP1 | |
| SCHEMBL7476540 | 0.88 | PTGER4 (0.73) | PTGER4PTGIRPTGER1PTGER3HDAC3 | |
| SCHEMBL7840686 | 0.88 | PTGIR (0.74) | PTGER4PTGIRPTGER1PTGER3PARP1 | |
| SCHEMBL7486168 | 0.88 | PTGER4 (0.70) | PTGER4PTGIRPTGER1PTGER3PARP1 | |
| SCHEMBL7486175 | 0.88 | PTGER4 (0.70) | PTGER4PTGIRPTGER1PTGER3PARP1 | |
| Hydrochloric Acid SCHEMBL7481069 | 0.87 | PTGER4 (0.69) | PTGER4PTGIRPTGER1PTGER3PARP1 | |
| Hydrochloric Acid SCHEMBL7481075 | 0.87 | PTGER4 (0.69) | PTGER4PTGIRPTGER1PTGER3PARP1 | |
| SCHEMBL7476217 | 0.87 | PTGIR (0.79) | PTGER4PTGIRPTGER1PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6437146-B1 | MESANGIAL PROLIFERATIVE GLOMERULONEPHRITIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-20 | — | — | US | disclosed |
| EP-1115712-A1 | OXAZOLE COMPOUNDS AS PROSTAGLANDIN E2 AGONISTS OR ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000018744-A1 | OXAZOLE COMPOUNDS AS PROSTAGLANDIN E2 AGONISTS OR ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-06 | — | — | WO | disclosed |