Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.69 |
| ▸ | PTGIR | P43119 | 4/20 | 0.69 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.69 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.58 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475495 | 0.93 | PTGER4 (0.78) | PTGER4PTGIRPTGER1PTGER3KDM5B | |
| SCHEMBL7477735 | 0.91 | PTGER4 (0.73) | PTGER4PTGIRPTGER1PTGER3PARP1 | |
| SCHEMBL7475010 | 0.89 | PTGER4 (0.68) | PTGER4PTGIRPTGER1PTGER3KDM4E | |
| SCHEMBL7842424 | 0.87 | PTGER4 (0.64) | PTGER4PTGIRPTGER1PTGER3KDM4E | |
| SCHEMBL7960001 | 0.87 | PTGIR (0.78) | PTGER4PTGIRPTGER1PTGER3KDM4E | |
| SCHEMBL7949540 | 0.87 | PTGER4 (0.69) | PTGER4PTGIRPTGER1PTGER3KDM4E | |
| SCHEMBL7840686 | 0.87 | PTGIR (0.74) | PTGER4PTGIRPTGER1PTGER3PARP1 | |
| SCHEMBL7476540 | 0.86 | PTGER4 (0.73) | PTGER4PTGIRPTGER1PTGER3KDM5B | |
| SCHEMBL7486175 | 0.85 | PTGER4 (0.70) | PTGER4PTGIRPTGER1PTGER3MEN1 | |
| SCHEMBL7486168 | 0.85 | PTGER4 (0.70) | PTGER4PTGIRPTGER1PTGER3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115712-A1 | OXAZOLE COMPOUNDS AS PROSTAGLANDIN E2 AGONISTS OR ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000018744-A1 | OXAZOLE COMPOUNDS AS PROSTAGLANDIN E2 AGONISTS OR ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-06 | — | — | WO | disclosed |