Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 3/20 | 0.34 |
| ▸ | KIF11 | P52732 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7476122 | 0.87 | MIF (0.38) | MIFHDAC6 | |
| SCHEMBL7475327 | 0.81 | CNR1 (0.33) | MIFMEN1KMT2APDE3BPDE3A | |
| SCHEMBL7471554 | 0.75 | GRIA1 (0.32) | MIF | |
| SCHEMBL7471004 | 0.75 | MIF (0.31) | MIFPDE3BPDE3A | |
| SCHEMBL7475040 | 0.68 | MIF (0.55) | MIFHDAC6 | |
| SCHEMBL31117000 | 0.63 | PDE3B (0.61) | PDE3BPDE3A | |
| SCHEMBL16157204 | 0.63 | PDE3B (0.61) | PDE3BPDE3A | |
| SCHEMBL9548375 | 0.58 | — | — | |
| SCHEMBL16157009 | 0.58 | PDE3B (0.76) | PDE3BPDE3A | |
| Oxalic Acid SCHEMBL20984672 | 0.57 | HTT (0.51) | CA1CA2CA9HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054874-B1 | SUBSTITUTED AMINOPHENYL ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS | UPJOHN CO (US) | 2002-08-28 | — | — | EP | disclosed |
| EP-1054874-A1 | SUBSTITUTED AMINOPHENYL ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 2000-11-29 | — | — | EP | disclosed |
| US-6069141-A | BACTERICIDES | PHARMACIA & UPJOHN COMPANY (US) | 2000-05-30 | — | — | US | disclosed |
| WO-1999041244-A1 | SUBSTITUTED AMINOPHENYL ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 1999-08-19 | — | — | WO | disclosed |