Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7476122 | 0.80 | MIF (0.38) | MIF | |
| SCHEMBL7475327 | 0.78 | CNR1 (0.33) | MIFPDE3BPDE3A | |
| SCHEMBL7471554 | 0.75 | GRIA1 (0.32) | MIF | |
| SCHEMBL7475038 | 0.75 | MIF (0.34) | MIFPDE3BPDE3A | |
| SCHEMBL7471008 | 0.75 | MIF (0.46) | MIF | |
| SCHEMBL7531253 | 0.58 | PDE3B (0.37) | PDE3BPDE3A | |
| SCHEMBL7470274 | 0.53 | MIF (0.52) | MIF | |
| SCHEMBL9548375 | 0.52 | — | — | |
| SCHEMBL7470351 | 0.51 | MIF (0.60) | MIF | |
| SCHEMBL3546557 | 0.50 | SMPD3 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054874-B1 | SUBSTITUTED AMINOPHENYL ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS | UPJOHN CO (US) | 2002-08-28 | — | — | EP | disclosed |
| US-6069141-A | BACTERICIDES | PHARMACIA & UPJOHN COMPANY (US) | 2000-05-30 | — | — | US | disclosed |