Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.33 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | MIF | P14174 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMPD3 | Q9NY59 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471554 | 0.85 | GRIA1 (0.32) | MIF | |
| SCHEMBL7476122 | 0.84 | MIF (0.38) | MIF | |
| SCHEMBL7475038 | 0.81 | MIF (0.34) | MIFPDE3BPDE3AMEN1KMT2A | |
| SCHEMBL7471004 | 0.78 | MIF (0.31) | MIFPDE3BPDE3A | |
| SCHEMBL7470274 | 0.69 | MIF (0.52) | MIFLMNA | |
| SCHEMBL7471632 | 0.64 | MIF (0.47) | MIF | |
| SCHEMBL8065082 | 0.63 | CCR1 (0.32) | CNR1CNR2LMNAMEN1KMT2A | |
| SCHEMBL7531253 | 0.61 | PDE3B (0.37) | PDE3BPDE3A | |
| SCHEMBL9042286 | 0.57 | ALDH1A1 (0.39) | TSHRLMNAKDM4E | |
| SCHEMBL172523 | 0.57 | ALDH1A1 (0.41) | CNR1CNR2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054874-B1 | SUBSTITUTED AMINOPHENYL ISOXAZOLINE DERIVATIVES USEFUL AS ANTIMICROBIALS | UPJOHN CO (US) | 2002-08-28 | — | — | EP | disclosed |