⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL965048 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL27337099 | 0.78 | CHRNB2 (0.36) | — | |
| SCHEMBL1712220 | 0.77 | — | — | |
| SCHEMBL6417326 | 0.77 | — | — | |
| SCHEMBL4230778 | 0.77 | ALOX5 (0.37) | — | |
| SCHEMBL18611261 | 0.77 | — | — | |
| SCHEMBL18123870 | 0.77 | — | — | |
| SCHEMBL15314795 | 0.76 | CHRNB2 (0.39) | — | |
| SCHEMBL8078665 | 0.76 | CHRNB2 (0.39) | — | |
| SCHEMBL7485231 | 0.75 | CHRNB2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1250332-A1 | INHIBITORS OF INTERLEUKIN 5 GENE EXPRESSION | Abbott Laboratories (US) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001044223-A1 | INHIBITORS OF INTERLEUKIN 5 GENE EXPRESSION | ABBOTT LABORATORIES (US) | 2001-06-21 | — | — | WO | disclosed |