Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.68 |
| ▸ | DRD4 | P21917 | 1/20 | 0.68 |
| ▸ | DRD3 | P35462 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472643 | 0.93 | DRD2 (0.60) | DRD2DRD4DRD3 | |
| SCHEMBL7476726 | 0.91 | DRD2 (0.56) | DRD2DRD4DRD3 | |
| SCHEMBL7474344 | 0.89 | DRD2 (0.56) | DRD2DRD4DRD3 | |
| SCHEMBL7478885 | 0.89 | DRD2 (0.54) | DRD2DRD4DRD3 | |
| SCHEMBL7474193 | 0.87 | DRD2 (0.67) | DRD2DRD4DRD3 | |
| SCHEMBL7473481 | 0.87 | DRD2 (0.53) | DRD2DRD4DRD3 | |
| SCHEMBL7457321 | 0.84 | DRD2 (0.49) | DRD2DRD4DRD3 | |
| SCHEMBL7458470 | 0.82 | DRD2 (0.48) | DRD2DRD4DRD3 | |
| SCHEMBL7477939 | 0.81 | DRD2 (0.59) | DRD2DRD4DRD3 | |
| SCHEMBL7478147 | 0.81 | DRD2 (1.00) | DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923551-B1 | 4-AMINOETHOXY INDOLONE DERIVATIVES | AMERICAN HOME PROD (US) | 2002-06-05 | — | — | EP | claimed |
| EP-0923551-A1 | 4-AMINOETHOXY INDOLONE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-06-23 | — | — | EP | claimed |
| US-5817690-A | ANTIDOPAMINE AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-10-06 | — | — | US | claimed |
| WO-1998008819-A1 | 4-AMINOETHOXY INDOLONE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-03-05 | — | — | WO | claimed |
| EP-0923551-B1 | 4-AMINOETHOXY INDOLONE DERIVATIVES | AMERICAN HOME PROD (US) | 2002-06-05 | — | — | EP | disclosed |
| US-5817690-A | ANTIDOPAMINE AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-10-06 | — | — | US | disclosed |