Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 1.00 |
| ▸ | DRD4 | P21917 | 4/20 | 1.00 |
| ▸ | DRD3 | P35462 | 4/20 | 1.00 |
| ▸ | HTR6 | P50406 | 4/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480072 | 0.89 | DRD2 (0.80) | DRD2DRD4DRD3HTR6 | |
| SCHEMBL7485710 | 0.86 | DRD2 (0.76) | DRD2DRD4DRD3HTR6 | |
| SCHEMBL21538147 | 0.81 | DRD2 (0.69) | DRD2DRD4DRD3HTR6 | |
| SCHEMBL7475432 | 0.81 | DRD2 (0.68) | DRD2DRD4DRD3 | |
| SCHEMBL7482710 | 0.81 | DRD2 (0.67) | DRD2DRD4DRD3 | |
| SCHEMBL5638400 | 0.80 | DRD2 (0.67) | DRD2DRD4DRD3 | |
| SCHEMBL7474193 | 0.80 | DRD2 (0.67) | DRD2DRD4DRD3 | |
| SCHEMBL7443236 | 0.78 | DRD2 (0.63) | DRD2DRD4DRD3 | |
| SCHEMBL9385747 | 0.78 | DRD2 (0.63) | DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL7443683 | 0.77 | DRD2 (0.62) | DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923551-B1 | 4-AMINOETHOXY INDOLONE DERIVATIVES | AMERICAN HOME PROD (US) | 2002-06-05 | — | — | EP | claimed |
| US-5817690-A | ANTIDOPAMINE AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-10-06 | — | — | US | claimed |
| EP-0923551-B1 | 4-AMINOETHOXY INDOLONE DERIVATIVES | AMERICAN HOME PROD (US) | 2002-06-05 | — | — | EP | disclosed |
| EP-0923551-A1 | 4-AMINOETHOXY INDOLONE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-06-23 | — | — | EP | disclosed |
| US-5817690-A | ANTIDOPAMINE AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-10-06 | — | — | US | disclosed |
| WO-1998008819-A1 | 4-AMINOETHOXY INDOLONE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-03-05 | — | — | WO | disclosed |