Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | SAT1 | P21673 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21657595 | 1.00 | KDM4E (0.40) | KDM4ERECQLCYP2C19MEN1GLA | |
| SCHEMBL21106559 | 1.00 | KDM4E (0.40) | KDM4ERECQLCYP2C19MEN1GLA | |
| SCHEMBL16394016 | 1.00 | KDM4E (0.40) | KDM4ERECQLCYP2C19MEN1GLA | |
| SCHEMBL1505133 | 0.95 | — | — | |
| Ammonia Solution, Strong SCHEMBL25225880 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL5058912 | 0.92 | — | — | |
| SCHEMBL3797316 | 0.92 | CYP2C19 (0.45) | KDM4ERECQLCYP2C19MEN1GLA | |
| SCHEMBL15858231 | 0.90 | CYP2C19 (0.46) | KDM4ERECQLCYP2C19MEN1GLA | |
| SCHEMBL10962985 | 0.89 | KDM4E (0.47) | KDM4ERECQLCYP2C19MEN1GLA | |
| SCHEMBL5933120 | 0.89 | KDM4E (0.47) | KDM4ERECQLCYP2C19MEN1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048536-A1 | Novel Substituted Diaryl Azepine Derivatives as Integrin Ligands | GENESTE HERVE | 2010-02-25 | — | — | US | disclosed |
| US-20070098676-A1 | FUNCTIONALLY DIVERSE MACROMOLECULES AND THEIR SYNTHESIS | THE TEXAS A&M UNIVERSITY SYSTEM | 2007-05-03 | — | — | US | disclosed |
| US-20070041933-A1 | Functionally Diverse Macromolecules and Their Synthesis | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-02-22 | — | — | US | disclosed |
| EP-0818512-B1 | Quinoline derivative and use of same | MITSUI CHEMICALS INC (JP) | 2002-10-02 | — | — | EP | disclosed |
| US-6407242-B1 | REACTING A PHTHALIMIDE COMPOUND WITH A QUINOLINE COMPOUND;ELECTROLUMINESCENCE | MITSUI CHEMICALS, INC. (JP) | 2002-06-18 | — | — | US | disclosed |
| US-6132640-A | ZINC COMPLEXES OF QUINOLINE | MITSUI CHEMICALS, INC. (JP) | 2000-10-17 | — | — | US | disclosed |
| EP-0818512-A1 | Quinoline derivative and use of same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1998-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048536-A1 | Novel Substituted Diaryl Azepine Derivatives as Integrin Ligands | ITGB3, ITGAL, ITGB4 | KDM4E 1561/4885RECQL 4441/4885CYP2C19 2893/4885 |
| US-20070041933-A1 | Functionally Diverse Macromolecules and Their Synthesis | ECPAS, PCNA, MRPS22 | KDM4E 3934/4885RECQL 2415/4885CYP2C19 4469/4885 |
| US-20070098676-A1 | FUNCTIONALLY DIVERSE MACROMOLECULES AND THEIR SYNTHESIS | ECPAS, PCNA, MRPS22 | KDM4E 3934/4885RECQL 2415/4885CYP2C19 4469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.