Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.62 |
| ▸ | CTSS | P25774 | 6/20 | 0.62 |
| ▸ | CTSB | P07858 | 2/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.58 |
| ▸ | PPARA | Q07869 | 7/20 | 0.54 |
| ▸ | PPARG | P37231 | 6/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 2/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8298606 | 1.00 | CTSK (0.62) | CTSKCTSSCTSBPTPN1PPARA | |
| SCHEMBL17194109 | 0.89 | PTPN1 (0.55) | CTSKCTSSCTSBPTPN1PPARA | |
| SCHEMBL15802510 | 0.89 | PTPN1 (0.55) | CTSKCTSSCTSBPTPN1PPARA | |
| SCHEMBL29301853 | 0.88 | CTSK (0.52) | CTSKCTSSCTSBPTPN1PPARA | |
| SCHEMBL29481445 | 0.88 | CTSS (0.74) | CTSKCTSSCTSBPTPN1PPARA | |
| SCHEMBL29401906 | 0.88 | CTSS (0.74) | CTSKCTSSCTSBPTPN1PPARA | |
| SCHEMBL3821361 | 0.88 | CTSS (0.74) | CTSKCTSSCTSBPTPN1PPARA | |
| SCHEMBL29397962 | 0.88 | CTSS (0.74) | CTSKCTSSCTSBPTPN1PPARA | |
| SCHEMBL29436862 | 0.88 | CTSS (0.74) | CTSKCTSSCTSBPTPN1PPARA | |
| SCHEMBL1519731 | 0.88 | CTSS (0.74) | CTSKCTSSCTSBPTPN1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937262-B1 | COMPOSITION FOR USE IN TREATING GASTROINTESTINAL DYSMOTILITY | IPSEN PHARMA (FR) | 2019-05-08 | — | — | EP | disclosed |
| EP-0923550-B1 | ACYLAMINOALKENYLENE-AMIDE DERIVATIVES AS NK1 AND NK2 ANTAGONISTS | NOVARTIS AG (CH) | 2002-09-25 | — | — | EP | disclosed |
| US-6319917-B1 | NEUROGENIC INFLAMMATION AND TACHYKININ BRONCHOCONSTRICTION INHIBITORS | NOVARTIS AG (CH) | 2001-11-20 | — | — | US | disclosed |